Small RNAs Are Trafficked from the Epididymis to Developing Mammalian Sperm
نویسندگان
چکیده
منابع مشابه
Small RNAs in early mammalian development: from gametes to gastrulation.
Small non-coding RNAs, including microRNAs (miRNAs), endogenous small interfering RNAs (endo-siRNAs) and Piwi-interacting RNAs (piRNAs), play essential roles in mammalian development. The function and timing of expression of these three classes of small RNAs differ greatly. piRNAs are expressed and play a crucial role during male gametogenesis, whereas endo-siRNAs are essential for oocyte meios...
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In mammals, transit through the epididymis, which involves the acquisition, loss and modification of proteins, is required to confer motility and fertilization competency to sperm. The overall dynamics of maturation is poorly understood, and a systems level understanding of the complex maturation process will provide valuable new information about changes occurring during epididymal transport. ...
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ژورنال
عنوان ژورنال: Developmental Cell
سال: 2018
ISSN: 1534-5807
DOI: 10.1016/j.devcel.2018.06.023